Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.55 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | LMNA | P02545 | 7/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455278 | 0.79 | RAB9A (0.69) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL5881545 | 0.78 | LMNA (0.63) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29780113 | 0.78 | LMNA (0.63) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29537831 | 0.74 | LMNA (0.58) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL1885546 | 0.74 | LMNA (0.58) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2853072 | 0.73 | LMNA (0.73) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL2853073 | 0.73 | LMNA (0.73) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL4397568 | 0.73 | MEN1 (0.51) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL29463677 | 0.72 | LMNA (0.65) | KMT2AMEN1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL18812865 | 0.72 | LMNA (0.65) | KMT2AMEN1LMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011023722-A1 | NOVEL QUINOXALINONE HEPCIDIN ANTAGONISTS | VIFOR (INTERNATIONAL) AG (CH) | 2011-03-03 | — | — | WO | disclosed |