SCHEMBL1496828

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3224606	0.95	TSHR (0.51)	TSHRMAPTHSD17B10USP2ALDH1A1
	SCHEMBL3234688	0.93	TSHR (0.49)	TSHRMAPTHSD17B10USP2ALDH1A1
	SCHEMBL1483058	0.91	TSHR (0.47)	TSHRMAPTHSD17B10USP2ALDH1A1
	SCHEMBL8004217	0.90	ALDH1A1 (0.47)	TSHRMAPTHSD17B10USP2ALDH1A1
	SCHEMBL1496956	0.89	USP2 (0.48)	TSHRMAPTHSD17B10USP2ALDH1A1
	SCHEMBL8000742	0.88	USP2 (0.47)	TSHRMAPTHSD17B10USP2ALDH1A1
	SCHEMBL3218279	0.88	TSHR (0.52)	TSHRMAPTHSD17B10USP2ALDH1A1
	SCHEMBL3223656	0.88	TSHR (0.44)	TSHRMAPTHSD17B10USP2ALDH1A1
	SCHEMBL1497051	0.88	MAPT (0.51)	TSHRMAPTHSD17B10USP2ALDH1A1
	SCHEMBL3227168	0.87	TSHR (0.61)	TSHRMAPTHSD17B10USP2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.