SCHEMBL14968290

SCHEMBL14968290

CCCCOC(=O)C1(C)OC12CCCC2

nearest known ligand 0.40

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
ATM Q13315 1/20 0.38
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
TSHR P16473 2/20 0.36
HPGD P15428 1/20 0.36
PSEN1 P49768 3/20 0.36
HCAR2 Q8TDS4 1/20 0.34
PRKCA P17252 5/20 0.33
NAAA Q02083 1/20 0.33
KDM4E B2RXH2 1/20 0.33
HSD17B10 Q99714 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14968107 0.98 ALDH1A1 (0.39) ALDH1A1ATMLMNAPOLBSMN1; SMN2
SCHEMBL14967808 0.97 ALDH1A1 (0.40) ALDH1A1ATMLMNAPOLBSMN1; SMN2
SCHEMBL14967418 0.95 PSEN1 (0.40) ALDH1A1TSHRPSEN1HCAR2PRKCA
SCHEMBL14968212 0.94 NAAA (0.42) TSHRPSEN1HCAR2PRKCANAAA
SCHEMBL14967845 0.94 PSEN1 (0.39) ALDH1A1TSHRPSEN1HCAR2PRKCA
SCHEMBL14967897 0.92 NAAA (0.41) TSHRPSEN1HCAR2PRKCANAAA
SCHEMBL14967935 0.92 PSEN1 (0.40) ALDH1A1TSHRPSEN1HCAR2PRKCA
SCHEMBL14968049 0.91 NAAA (0.42) TSHRPSEN1HCAR2PRKCANAAA
SCHEMBL14967478 0.90 TSHR (0.33) ALDH1A1LMNAPOLBMEN1KMT2A
SCHEMBL14967317 0.89 TSHR (0.35) ALDH1A1LMNAPOLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US claimed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US claimed
US-10301397-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2019-05-28 US disclosed
US-20160340447-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2016-11-24 US disclosed
US-9458270-B2 Method for producing polydienes and polydiene copolymers with reduced cold flow BRIDGESTONE CORPORATION (JP) 2016-10-04 US disclosed
EP-2780177-B1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORP (JP) 2016-03-23 EP disclosed
US-20140296445-A1 Method For Producing Polydienes And Polydiene Copolymers With Reduced Cold Flow BRIDGESTONE CORPORATION (JP) 2014-10-02 US disclosed
EP-2780177-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW Bridgestone Corporation (JP) 2014-09-24 EP disclosed
WO-2013075074-A1 METHOD FOR PRODUCING POLYDIENES AND POLYDIENE COPOLYMERS WITH REDUCED COLD FLOW BRIDGESTONE CORPORATION (JP) 2013-05-23 WO disclosed