SCHEMBL1496839

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496985	0.90	USP2 (0.45)	TSHRUSP2POLBROCK2HSD17B10
	SCHEMBL1496989	0.90	TSHR (0.52)	TSHRALDH1A1KDM4EHPGDGLA
	SCHEMBL1497445	0.89	KDM4E (0.40)	TSHRALDH1A1KDM4EHPGDGLA
	SCHEMBL1496851	0.89	USP2 (0.45)	TSHRALDH1A1KDM4EMAPTTP53
	SCHEMBL1496867	0.88	USP2 (0.43)	TSHRUSP2KMT2APOLBROCK2
	SCHEMBL8004861	0.88	USP2 (0.45)	TSHRUSP2KMT2APOLBROCK2
	SCHEMBL1497016	0.87	USP2 (0.43)	TSHRALDH1A1KDM4EMAPTTP53
	SCHEMBL1496922	0.87	USP2 (0.43)	TSHRALDH1A1KDM4EMAPTTP53
	SCHEMBL8001525	0.86	POLB (0.42)	TSHRALDH1A1KDM4EHPGDMAPT
	SCHEMBL3218367	0.85	USP2 (0.46)	TSHRALDH1A1KDM4EHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.