SCHEMBL1497445

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3234400	0.94	HSD17B10 (0.44)	KDM4EALDH1A1HPGDHSD17B10EPHX2
	SCHEMBL9915261	0.91	ALK (0.37)	ALDH1A1SMN1; SMN2TP53IDO1NPC1
	SCHEMBL1496985	0.90	USP2 (0.45)	HSD17B10USP2TSHRCD274OPRM1
	SCHEMBL1496839	0.89	TSHR (0.50)	KDM4EALDH1A1HPGDHSD17B10USP2
	SCHEMBL1497047	0.88	KDM4E (0.40)	KDM4EALDH1A1HPGDHSD17B10EPHX2
	SCHEMBL1496851	0.88	USP2 (0.45)	KDM4EALDH1A1USP2LMNAMAPT
	SCHEMBL1496867	0.88	USP2 (0.43)	HSD17B10USP2TSHRCD274OPRM1
	SCHEMBL7997914	0.88	FAAH (0.38)	ALDH1A1HPGDSMN1; SMN2GAAIDO1
	SCHEMBL8000742	0.87	USP2 (0.47)	KDM4EALDH1A1HPGDHSD17B10USP2
	SCHEMBL8004861	0.87	USP2 (0.45)	HSD17B10USP2TSHRCD274OPRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.