Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | USP2 | O75604 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.66 |
| ▸ | CASP1 | P29466 | 1/20 | 0.66 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.66 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.66 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468192 | 0.89 | SMN1; SMN2 (0.56) | MEN1KMT2ACYP3A4SMN1; SMN2LMNA | |
| SCHEMBL466186 | 0.89 | SMN1; SMN2 (0.56) | MEN1KMT2ACYP3A4SMN1; SMN2LMNA | |
| SCHEMBL5473974 | 0.89 | SMN1; SMN2 (0.56) | MEN1KMT2ACYP3A4SMN1; SMN2LMNA | |
| SCHEMBL5462324 | 0.89 | SMN1; SMN2 (0.56) | MEN1KMT2ACYP3A4SMN1; SMN2LMNA | |
| SCHEMBL5459507 | 0.89 | SMN1; SMN2 (0.56) | MEN1KMT2ACYP3A4SMN1; SMN2LMNA | |
| SCHEMBL5457352 | 0.89 | SMN1; SMN2 (0.56) | MEN1KMT2ACYP3A4SMN1; SMN2LMNA | |
| SCHEMBL12516024 | 0.89 | ALDH1A1 (0.51) | MEN1KMT2ACYP3A4SMN1; SMN2LMNA | |
| SCHEMBL466179 | 0.88 | SMN1; SMN2 (0.58) | MEN1KMT2ACYP3A4SMN1; SMN2LMNA | |
| SCHEMBL13227405 | 0.86 | NR5A1 (0.61) | SMN1; SMN2LMNAMAPTNR5A1TP53 | |
| SCHEMBL10013798 | 0.86 | NR5A1 (0.61) | SMN1; SMN2LMNAMAPTNR5A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9388112-B2 | Bisphenol derivatives and their use as androgen receptor activity modulators | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2016-07-12 | — | — | US | disclosed |
| US-20130131167-A1 | BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131167-A1 | BISPHENOL DERIVATIVES AND THEIR USE AS ANDROGEN RECEPTOR ACTIVITY MODULATORS | CYP19A1, AR, SHBG | MEN1 1113/4885KMT2A 3079/4885CYP3A4 853/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.