Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14968808 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2 | |
| SCHEMBL14964872 | 0.77 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4ETP53 | |
| SCHEMBL14964873 | 0.76 | KDM4E (0.54) | SMN1; SMN2KDM4E | |
| SCHEMBL14965005 | 0.75 | LMNA (0.64) | — | |
| SCHEMBL14965111 | 0.75 | — | — | |
| SCHEMBL14964830 | 0.74 | SMN1; SMN2 (0.56) | SMN1; SMN2 | |
| SCHEMBL14965160 | 0.74 | — | — | |
| SCHEMBL14965098 | 0.73 | SMN1; SMN2 (0.46) | SMN1; SMN2 | |
| SCHEMBL14965434 | 0.73 | SMN1; SMN2 (0.44) | SMN1; SMN2KDM4ETP53 | |
| SCHEMBL14965426 | 0.72 | SMN1; SMN2 (0.47) | SMN1; SMN2KDM4ETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780343-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | Xention Limited (GB) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072694-A1 | THIENO- AND FURO - PYRIMIDINES AND PYRIDINES, USEFUL AS POTASSIUM CHANNEL INHIBITORS | XENTION LIMITED (GB) | 2013-05-23 | — | — | WO | disclosed |