SCHEMBL1496884

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496970	0.96	GAA (0.39)	GAAACVR1PDCD1CD274HTR5A
	SCHEMBL1496938	0.95	GAA (0.50)	GAAACVR1PDCD1CD274HTR5A
	SCHEMBL4224190	0.89	HDAC1 (0.45)	GAAACVR1PDCD1CD274HTR5A
	SCHEMBL1497054	0.88	GAA (0.45)	GAAACVR1APOBEC3ACTDSP1APOBEC3G
	SCHEMBL4224312	0.88	GAA (0.45)	GAAACVR1PDCD1CD274HTR5A
	SCHEMBL1482918	0.87	KDM4E (0.43)	GAAACVR1ROCK1KDM4ETSHR
	SCHEMBL1497121	0.87	KDM4E (0.40)	GAAACVR1PDCD1CD274APOBEC3A
	SCHEMBL1497176	0.86	PDCD1 (0.39)	PDCD1CD274ROCK1ROCK2HDAC3
	SCHEMBL1496850	0.86	GAA (0.41)	GAAACVR1PDCD1CD274HTR5A
	SCHEMBL1497098	0.86	KDM4E (0.39)	GAAACVR1APOBEC3ACTDSP1APOBEC3G

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.