SCHEMBL1497121

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1496952	0.95	SLC2A1 (0.42)	KDM4EUSP2ALDH1A1ALOX15KMT2A
	SCHEMBL1482918	0.94	KDM4E (0.43)	KDM4EUSP2ALDH1A1ALOX15KMT2A
	SCHEMBL1496881	0.91	KDM4E (0.44)	KDM4EUSP2ALDH1A1ALOX15KMT2A
	SCHEMBL1497098	0.90	KDM4E (0.39)	KDM4EUSP2ALDH1A1ALOX15KMT2A
	SCHEMBL1496943	0.88	KCNH2 (0.38)	ALDH1A1KMT2AMEN1GAACYP1A2
	SCHEMBL1496831	0.87	KDM4E (0.38)	KDM4EUSP2ALDH1A1ALOX15KMT2A
	SCHEMBL1482709	0.87	KDM4E (0.45)	KDM4EUSP2ALDH1A1KMT2ABMPR1B
	SCHEMBL1496884	0.87	GAA (0.43)	KDM4EALDH1A1KMT2AMEN1ACVR1
	SCHEMBL1496929	0.86	ALDH1A1 (0.39)	KDM4EUSP2ALDH1A1KMT2AMEN1
	SCHEMBL1496957	0.86	KDM4E (0.43)	KDM4EUSP2ALDH1A1KMT2ABMPR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.