Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MAPT | P10636 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.31 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31415058 | 1.00 | MEN1 (0.37) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL14966103 | 1.00 | MEN1 (0.37) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL16596970 | 1.00 | MEN1 (0.37) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL24297214 | 0.89 | ALDH1A1 (0.36) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL16596969 | 0.86 | MEN1 (0.39) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL14966026 | 0.86 | MEN1 (0.39) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL14968879 | 0.86 | MEN1 (0.39) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL30871812 | 0.85 | MEN1 (0.38) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL31555294 | 0.85 | MEN1 (0.38) | MEN1KMT2AMAPTALDH1A1L3MBTL1 | |
| SCHEMBL1742069 | 0.85 | MEN1 (0.38) | MEN1KMT2AMAPTALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9440927-B2 | Process for preparation of substituted 3'-hydroazino-diphenyl-3-carboxylic acid compounds | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2016-09-13 | — | — | US | disclosed |
| US-20150087845-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED 3'-HYDROAZINO-DIPHENYL-3-CARBOXYLIC ACID COMPOUNDS | GLENMARK GENERICS LIMITED (IN) | 2015-03-26 | — | — | US | disclosed |
| EP-2755955-A2 | PROCESS FOR PREPARATION OF SUBSTITUTED 3'-HYDRAZINO-BIPHENYL-3-CARBOXYLIC ACID COMPOUNDS | Glenmark Generics Limited (IN) | 2014-07-23 | — | — | EP | disclosed |
| WO-2013072921-A2 | PROCESS FOR PREPARATION OF SUBSTITUTED 3'-HYDRAZINO-BIPHENYL-3-CARBOXYLIC ACID COMPOUNDS | GLENMARK GENERICS LIMITED (IN) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150087845-A1 | PROCESS FOR PREPARATION OF SUBSTITUTED 3'-HYDROAZINO-DIPHENYL-3-CARBOXYLIC ACID COMPOUNDS | CYP3A5, UGT1A3, HPD | MEN1 3749/4885KMT2A 702/4885MAPT 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.