SCHEMBL1496906

SCHEMBL1496906

CC(C)NC(=O)NC(CCN(C)C)c1ccc(C(=O)Nc2cscc2N)cc1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1482616 0.87 UTS2R (0.41) UTS2R
SCHEMBL1497110 0.87 UTS2R (0.47) UTS2R
SCHEMBL10476398 0.84 UTS2R (0.43) UTS2R
SCHEMBL1496984 0.84 UTS2R (0.49) UTS2R
SCHEMBL1482524 0.83 UTS2R (0.45) UTS2R
SCHEMBL10476439 0.82 UTS2R (0.41) UTS2R
SCHEMBL1497187 0.78 UTS2R (0.42) UTS2R
SCHEMBL1496910 0.77 UTS2R (0.41) UTS2R
SCHEMBL3834409 0.77 UTS2R (0.49) UTS2R
SCHEMBL1496900 0.76 PTGES (0.44)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2292611-B1 NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE SANTEN PHARMACEUTICAL CO LTD (JP) 2012-07-25 EP disclosed
EP-2292611-A1 NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE Santen Pharmaceutical Co., Ltd (JP) 2011-03-09 EP disclosed