Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | PLK1 | P53350 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.63 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 5/20 | 0.63 |
| ▸ | NPC1 | O15118 | 5/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13702374 | 0.87 | KMT2A (0.69) | SMN1; SMN2KMT2APLK1LMNANR1H4 | |
| SCHEMBL6154011 | 0.87 | SMN1; SMN2 (0.65) | SMN1; SMN2KMT2ALMNANR1H4HTT | |
| SCHEMBL24500604 | 0.86 | SMPD1 (0.70) | KMT2APLK1NR1H4ALDH1A1MAPK1 | |
| SCHEMBL30111865 | 0.85 | HDAC8 (0.53) | SMN1; SMN2KMT2ALMNANR1H4HTT | |
| SCHEMBL14997388 | 0.85 | HDAC8 (0.53) | SMN1; SMN2KMT2APLK1LMNANR1H4 | |
| SCHEMBL13702271 | 0.85 | SMN1; SMN2 (0.63) | SMN1; SMN2KMT2ALMNANR1H4HTT | |
| SCHEMBL30184164 | 0.84 | HPGD (0.63) | SMN1; SMN2KMT2ALMNANR1H4HTT | |
| SCHEMBL13753371 | 0.84 | ALDH1A1 (0.71) | SMN1; SMN2KMT2ALMNANR1H4HTT | |
| SCHEMBL30099037 | 0.84 | SMPD1 (0.56) | SMN1; SMN2KMT2ALMNANR1H4HTT | |
| SCHEMBL31194774 | 0.83 | SMPD1 (0.80) | KMT2ANR1H4MAPK1KAT6A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023288033-A1 | ASGPR CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | LYCIA THERAPEUTICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | MORITA KOHEI (JP) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | PLA2G12A, PLA2G4A, PLA2G4B | SMN1; SMN2 3036/4885KMT2A 1631/4885PLK1 1861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.