Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 5/20 | 0.87 |
| ▸ | RARB | P10826 | 5/20 | 0.61 |
| ▸ | THRA | P10827 | 5/20 | 0.61 |
| ▸ | THRB | P10828 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | RARA | P10276 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | MTOR | P42345 | 1/20 | 0.61 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.60 |
| ▸ | PLK3 | Q9H4B4 | 2/20 | 0.58 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.58 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23484726 | 0.95 | PLK1 (0.79) | PLK1RARBTHRATHRBMEN1 | |
| SCHEMBL6958590 | 0.93 | PLK1 (1.00) | PLK1RARBTHRATHRBALDH1A1 | |
| SCHEMBL21628877 | 0.91 | PLK1 (0.72) | PLK1RARBTHRATHRBMEN1 | |
| SCHEMBL21628518 | 0.89 | PLK1 (0.74) | PLK1RARBTHRBPLK3 | |
| SCHEMBL9504756 | 0.86 | HDAC1 (0.73) | PLK1RARBTHRATHRBMEN1 | |
| SCHEMBL28709309 | 0.86 | PLK1 (0.65) | PLK1RARBTHRATHRBMEN1 | |
| SCHEMBL9206725 | 0.86 | PLK1 (0.65) | PLK1RARBTHRATHRBMEN1 | |
| SCHEMBL4824490 | 0.86 | PLK1 (0.65) | PLK1RARBTHRATHRBMEN1 | |
| SCHEMBL9164847 | 0.86 | PLK1 (0.65) | PLK1RARBTHRATHRBMEN1 | |
| SCHEMBL15174597 | 0.86 | PLK1 (0.65) | PLK1RARBTHRATHRBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | MORITA KOHEI (JP) | 2013-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131134-A1 | PHENYLPROPIONIC ACID DERIVATIVE AND USE THEREOF | PLA2G12A, PLA2G4A, PLA2G4B | PLK1 1861/4885RARB 2328/4885THRA 3096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.