Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 1/20 | 0.48 |
| ▸ | STK17B | O94768 | 1/20 | 0.45 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.45 |
| ▸ | KDM4A | O75164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966057 | 0.85 | PTGES (0.39) | ATRTSHRKDM4ELMNA | |
| SCHEMBL26657670 | 0.83 | STK17B (0.47) | STK17BSTK17AKDM4ACA12CA1 | |
| SCHEMBL30670723 | 0.83 | STK17B (0.47) | STK17BSTK17AKDM4ACA12CA1 | |
| SCHEMBL22828361 | 0.79 | STK17B (0.44) | STK17BSTK17AKDM4APOLBMAPK1 | |
| SCHEMBL5270836 | 0.78 | ATR (0.51) | ATRSTK17BSTK17AKDM4ACA12 | |
| SCHEMBL30381133 | 0.78 | ATR (0.54) | ATRSTK17BSTK17ACA12CA1 | |
| SCHEMBL29546939 | 0.77 | STK17B (0.45) | ATRSTK17BSTK17AKDM4ACA12 | |
| SCHEMBL18567056 | 0.77 | STK17B (0.45) | ATRSTK17BSTK17AKDM4ACA12 | |
| SCHEMBL14969490 | 0.77 | TSHR (0.57) | ATRL3MBTL1TSHRLMNA | |
| SCHEMBL24770163 | 0.77 | ALDH1A1 (0.40) | POLBATMTSHRKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072825-A1 | PHTALAZINONE DERIVATIVES AS MPEGS -1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072825-A1 | PHTALAZINONE DERIVATIVES AS MPEGS -1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-05-23 | — | — | WO | disclosed |