Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR3 | P49682 | 6/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | LCAT | P04180 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14966286 | 0.92 | CXCR3 (0.42) | CXCR3NR1H2NR1H3SLC6A9KCNH2 | |
| SCHEMBL14970181 | 0.88 | CXCR3 (0.41) | CXCR3NR1H2NR1H3SLC6A9KCNH2 | |
| SCHEMBL14966416 | 0.81 | KCNH2 (0.45) | CXCR3NR1H2NR1H3SLC6A9KCNH2 | |
| SCHEMBL14969474 | 0.80 | CXCR3 (0.40) | CXCR3NR1H2NR1H3SLC6A9KCNH2 | |
| SCHEMBL14966354 | 0.80 | CXCR3 (0.42) | CXCR3NR1H2NR1H3SLC6A9KCNH2 | |
| SCHEMBL14969497 | 0.79 | SLC6A9 (0.43) | CXCR3NR1H2NR1H3SLC6A9KCNH2 | |
| SCHEMBL14969473 | 0.79 | NR1H2 (0.43) | CXCR3NR1H2NR1H3SLC6A9KCNH2 | |
| SCHEMBL14969317 | 0.79 | KCNH2 (0.43) | CXCR3NR1H2NR1H3SLC6A9KCNH2 | |
| SCHEMBL14966702 | 0.78 | SLC6A9 (0.44) | CXCR3NR1H2NR1H3SLC6A9KCNH2 | |
| SCHEMBL14966287 | 0.78 | CXCR3 (0.41) | CXCR3NR1H2NR1H3SLC6A9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074641-A1 | PIPERIDINYL- SUBSTITUTED CYCLIC UREAS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2013-05-23 | — | — | WO | disclosed |