Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | CCR6 | P51684 | 2/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14969487 | 1.00 | KDM4E (0.50) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL571782 | 1.00 | KDM4E (0.50) | KDM4EALOX12CYP3A4TDP1PKM | |
| Water SCHEMBL6469700 | 0.99 | KDM4E (0.49) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL16394163 | 0.87 | MAPT (0.39) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL599824 | 0.85 | KDM4E (0.54) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL29456554 | 0.85 | KDM4E (0.54) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL14969486 | 0.79 | KDM4E (0.53) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL571781 | 0.79 | KDM4E (0.53) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL600529 | 0.79 | KDM4E (0.47) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL28956303 | 0.79 | KDM4E (0.58) | KDM4EALOX12CYP3A4TDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780323-A1 | PROCESS FOR THE PREPARATION OF A QUINOLINE CARBOXYLIC ACID | Syngenta Participations AG (CH) | 2014-09-24 | — | — | EP | disclosed |
| WO-2013072376-A1 | PROCESS FOR THE PREPARATION OF A QUINOLINE CARBOXYLIC ACID | SYNGENTA PARTICIPATIONS AG (CH) | 2013-05-23 | — | — | WO | disclosed |