Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | CCR6 | P51684 | 2/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL599824 | 1.00 | KDM4E (0.54) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL14969487 | 0.85 | KDM4E (0.50) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL571782 | 0.85 | KDM4E (0.50) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL14969485 | 0.85 | KDM4E (0.50) | KDM4EALOX12CYP3A4TDP1PKM | |
| Water SCHEMBL6469700 | 0.84 | KDM4E (0.49) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL600529 | 0.82 | KDM4E (0.47) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL571602 | 0.82 | KDM4E (0.63) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL168947 | 0.79 | KDM4E (0.62) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL571223 | 0.79 | KDM4E (0.59) | KDM4EALOX12CYP3A4TDP1PKM | |
| SCHEMBL9282530 | 0.77 | KDM4E (0.59) | KDM4EALOX12CYP3A4TDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115702157-A | Substituted pyrrolin-2-ones and their use as herbicides | 拜耳公司 | 2023-02-14 | — | — | CN | disclosed |
| WO-2022095816-A1 | TERNARY HERBICIDAL COMPOSITION COMPRISING CARBOXYLIC ACID DERIVATIVE-SUBSTITUTED OXYIMINOARYL COMPOUND AND USE THEREOF | 青岛清原化合物有限公司 | 2022-05-12 | — | — | WO | disclosed |
| WO-2022068377-A1 | BINARY HERBICIDAL COMPOSITION AND USE THEREOF | 青岛清原化合物有限公司 | 2022-04-07 | — | — | WO | disclosed |