Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | CCR6 | P51684 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29456554 | 0.82 | KDM4E (0.54) | KDM4EALOX12TDP1CYP3A4PKM | |
| SCHEMBL599824 | 0.82 | KDM4E (0.54) | KDM4EALOX12TDP1CYP3A4PKM | |
| SCHEMBL28455383 | 0.80 | KDM4E (0.55) | KDM4EALOX12TDP1CYP3A4PKM | |
| SCHEMBL600528 | 0.79 | KDM4E (0.48) | KDM4EALOX12TDP1CYP3A4PKM | |
| SCHEMBL14969487 | 0.79 | KDM4E (0.50) | KDM4EALOX12TDP1CYP3A4PKM | |
| SCHEMBL571782 | 0.79 | KDM4E (0.50) | KDM4EALOX12TDP1CYP3A4PKM | |
| SCHEMBL14969485 | 0.79 | KDM4E (0.50) | KDM4EALOX12TDP1CYP3A4PKM | |
| SCHEMBL29514512 | 0.78 | PKM (0.53) | KDM4EALOX12TDP1CYP3A4PKM | |
| SCHEMBL341876 | 0.78 | PKM (0.53) | KDM4EALOX12TDP1CYP3A4PKM | |
| SCHEMBL571602 | 0.78 | KDM4E (0.63) | KDM4EALOX12TDP1CYP3A4PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8629084-B2 | Iodine-phenyl-substituted cyclic cetoenols | BAYER CROPSCIENCE AG (DE) | 2014-01-14 | — | — | US | claimed |
| US-20110130284-A1 | CIS-ALKOXYSPIROCYCLIC BIPHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2011-06-02 | — | — | US | claimed |
| US-5622910-A | CROP PROTECTION AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | claimed |
| US-20230167088-A1 | 1-PYRAZINYLPYRAZOLYL-3-OXYALKYL ACIDS AND THEIR DERIVATIVES, AND THEIR USE FOR CONTROL OF UNDESIRED PLANT GROWTH | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-01 | — | — | US | disclosed |
| US-20230159472-A1 | SUBSTITUTED ISOPHTHALIC ACID DIAMIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2023-05-25 | — | — | US | disclosed |
| US-20230126893-A1 | [(1,4,5-TRISUBSTITUTED-1H-PYRAZOL-3-YL)SULFANYL]ACETIC ACID DERIVATIVES, SALTS THEREOF, AND USE THEREOF AS ACTIVE HERBICIDAL INGREDIENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-04-27 | — | — | US | disclosed |
| US-20220264878-A1 | HERBICIDAL COMPOSITION CONTAINING R-TYPE PYRIDYLOXY CARBOXYLIC ACID DERIVATIVE AND USE THEREOF | QINGDAO KINGAGROOT CHEMICAL COMPOUND CO., LTD. (CN) | 2022-08-25 | — | — | US | disclosed |
| EP-4005384-A1 | HERBICIDAL COMPOSITION CONTAINING R-TYPE PYRIDYLOXY CARBOXYLIC ACID DERIVATIVE AND USE THEREOF | Qingdao KingAgroot Chemical Compound Co., Ltd. (CN) | 2022-06-01 | — | — | EP | disclosed |
| US-20200404914-A1 | HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES | BAYER AG (DE) | 2020-12-31 | — | — | US | disclosed |
| US-10869478-B2 | Uses of 2-(2,4-dichlorophenyl)methyl-4,4-dimethyl-3-isoxazolidone as foliar herbicide | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-12-22 | — | — | US | disclosed |
| US-20200085055-A1 | New uses of 2-(2,4-dichlorophenyl)methyl-4,4-dimethyl-3-isoxazolidone as foliar herbicide | FMC CORPORATION | 2020-03-19 | — | — | US | disclosed |
| US-7135434-B2 | Herbicidally active composition comprising a mixture of A. a herbicidally active amount of one or more compounds of the | HOECHST SCHERING AGREVO GMBH (DE) | 2006-11-14 | — | — | US | disclosed |
| US-20060240984-A1 | Herbicidal compositions | PALLETT KEN | 2006-10-26 | — | — | US | disclosed |
| US-7101827-B2 | Herbicides comprising benzoylcyclohexanediones and safeners | AVENTIS CROPSCIENCE GMBH (DE) | 2006-09-05 | — | — | US | disclosed |
| US-20050233906-A1 | Oil suspension concentrate | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-10-20 | — | — | US | disclosed |
| US-20050070437-A1 | Herbicide combinations comprising specific sulfonamides | BAYER CROPSCIENCE GMBH (DE) | 2005-03-31 | — | — | US | disclosed |
| US-6864217-B2 | Herbicidal compositions with substituted phenylsulfonylureas for controlling weeds in rice | HOECHST SCHERING AGREVO GMBH (DE) | 2005-03-08 | — | — | US | disclosed |
| US-20040224848-A1 | Herbicides comprising benzoylcyclohexanediones and safeners | AVENTIS CROPSCIENCE GMBH (DE) | 2004-11-11 | — | — | US | disclosed |
| US-20040157739-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | BAYER CROPSCIENCE AG (DE) | 2004-08-12 | — | — | US | disclosed |
| US-20020016263-A1 | Liquid formulations | AVENTIS CROPSCIENCE GMBH (DE) | 2002-02-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060240984-A1 | Herbicidal compositions | DDT, GLRX3, GPX1 | KDM4E 2233/4885ALOX12 2360/4885TDP1 2575/4885 |
| US-20050070437-A1 | Herbicide combinations comprising specific sulfonamides | DDT, B2M, MTX2 | KDM4E 4686/4885ALOX12 580/4885TDP1 4498/4885 |
| US-10869478-B2 | Uses of 2-(2,4-dichlorophenyl)methyl-4,4-dimethyl-3-isoxazolidone as foliar herbicide | DDT, DRD4, DAO | KDM4E 138/4885ALOX12 1529/4885TDP1 2656/4885 |
| US-20040157739-A1 | Amino-1,3,5-triazines N-substituted with chiral bicyclic radicals, process for their preparation, compositions thereof, and their use as herbicides and plant growth regulators | CYP4Z1, IL4I1, BCAT1 | KDM4E 743/4885ALOX12 2707/4885TDP1 2791/4885 |
| US-20230167088-A1 | 1-PYRAZINYLPYRAZOLYL-3-OXYALKYL ACIDS AND THEIR DERIVATIVES, AND THEIR USE FOR CONTROL OF UNDESIRED PLANT GROWTH | AGPS, CBR3, HPD | KDM4E 3651/4885ALOX12 1279/4885TDP1 2806/4885 |
| US-20230126893-A1 | [(1,4,5-TRISUBSTITUTED-1H-PYRAZOL-3-YL)SULFANYL]ACETIC ACID DERIVATIVES, SALTS THEREOF, AND USE THEREOF AS ACTIVE HERBICIDAL INGREDIENTS | SYMPK, ALDH7A1, AADAC | KDM4E 1517/4885ALOX12 1480/4885TDP1 2462/4885 |
| US-20200404914-A1 | HERBICIDALLY ACTIVE BICYCLIC BENZAMIDES | CBR3, CBR1, AOX1 | KDM4E 3993/4885ALOX12 1134/4885TDP1 2148/4885 |
| US-20110130284-A1 | CIS-ALKOXYSPIROCYCLIC BIPHENYL-SUBSTITUTED TETRAMIC ACID DERIVATIVES | DDT, AGXT, ABCC5 | KDM4E 1990/4885ALOX12 2330/4885TDP1 1817/4885 |
| US-20020016263-A1 | Liquid formulations | SLC25A1, SLC16A1, OTC | KDM4E 2261/4885ALOX12 783/4885TDP1 172/4885 |
| US-20200085055-A1 | New uses of 2-(2,4-dichlorophenyl)methyl-4,4-dimethyl-3-isoxazolidone as foliar herbicide | DDT, DAO, CYP4X1 | KDM4E 158/4885ALOX12 1621/4885TDP1 2290/4885 |
| US-20230159472-A1 | SUBSTITUTED ISOPHTHALIC ACID DIAMIDES | DDT, IDH2, DAO | KDM4E 2190/4885ALOX12 2349/4885TDP1 1738/4885 |
| US-20040224848-A1 | Herbicides comprising benzoylcyclohexanediones and safeners | DDT, HPD, HDHD5 | KDM4E 3009/4885ALOX12 663/4885TDP1 1227/4885 |
| US-20050233906-A1 | Oil suspension concentrate | TST, PFAS, STS | KDM4E 1810/4885ALOX12 102/4885TDP1 2053/4885 |
| US-20220264878-A1 | HERBICIDAL COMPOSITION CONTAINING R-TYPE PYRIDYLOXY CARBOXYLIC ACID DERIVATIVE AND USE THEREOF | HPD, DDT, CLPP | KDM4E 3625/4885ALOX12 309/4885TDP1 921/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.