Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ATR | Q13535 | 1/20 | 0.39 |
| ▸ | PYGL | P06737 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23583038 | 0.90 | ATR (0.41) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL24515278 | 0.84 | MTNR1A (0.47) | TSHRALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL23582943 | 0.83 | ALDH1A1 (0.40) | CYP4A11TSHRALDH1A1HPGDMAPT | |
| SCHEMBL14966521 | 0.82 | FFAR4 (0.51) | CYP4F2CYP4A11TSHRALDH1A1LMNA | |
| SCHEMBL23582768 | 0.82 | FFAR4 (0.44) | TSHRALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL14966304 | 0.81 | ALDH1A1 (0.48) | CYP4F2CYP4A11TSHRALDH1A1LMNA | |
| SCHEMBL24893924 | 0.81 | FFAR4 (0.43) | CYP4F2CYP4A11MEN1KMT2APYGL | |
| SCHEMBL15471912 | 0.80 | CYP4F2 (0.46) | CYP4F2CYP4A11TSHRALDH1A1LMNA | |
| SCHEMBL1905729 | 0.80 | NPC1 (0.41) | CYP4F2CYP4A11ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL14969490 | 0.79 | TSHR (0.57) | CYP4F2CYP4A11TSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013072825-A1 | PHTALAZINONE DERIVATIVES AS MPEGS -1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-05-23 | — | — | WO | disclosed |
| WO-2013072825-A1 | PHTALAZINONE DERIVATIVES AS MPEGS -1 INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2013-05-23 | — | — | WO | disclosed |