Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 16/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483181 | 0.95 | UTS2R (0.47) | HIF1AUTS2RROCK2ROCK1 | |
| SCHEMBL1497005 | 0.91 | UTS2R (0.42) | HIF1AUTS2R | |
| SCHEMBL1497037 | 0.91 | UTS2R (0.38) | HIF1AUTS2R | |
| SCHEMBL1496894 | 0.91 | UTS2R (0.46) | UTS2R | |
| SCHEMBL1497206 | 0.89 | UTS2R (0.46) | UTS2R | |
| SCHEMBL10476396 | 0.88 | UTS2R (0.42) | HIF1AUTS2RROCK2ROCK1 | |
| SCHEMBL1497076 | 0.87 | UTS2R (0.40) | UTS2R | |
| SCHEMBL4224174 | 0.86 | UTS2R (0.49) | HIF1AUTS2R | |
| SCHEMBL1496981 | 0.86 | HIF1A (0.44) | HIF1AUTS2R | |
| SCHEMBL1496939 | 0.85 | UTS2R (0.38) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-B1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |