Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 11/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483181 | 0.95 | UTS2R (0.47) | UTS2RHIF1AMEN1TSHRKMT2A | |
| SCHEMBL1496894 | 0.92 | UTS2R (0.46) | UTS2REPHX2HDAC1 | |
| SCHEMBL2385692 | 0.91 | HDAC1 (0.45) | UTS2RHIF1AEPHX2HDAC3HDAC1 | |
| SCHEMBL1497017 | 0.91 | HIF1A (0.46) | UTS2RHIF1A | |
| SCHEMBL1497037 | 0.87 | UTS2R (0.38) | UTS2RHIF1AHDAC3HDAC1HDAC2 | |
| SCHEMBL1496899 | 0.87 | CTSK (0.40) | UTS2RHIF1AEPHX2MEN1KMT2A | |
| SCHEMBL1497076 | 0.87 | UTS2R (0.40) | UTS2R | |
| SCHEMBL1496898 | 0.86 | HDAC3 (0.38) | HIF1AEPHX2KMT2AHDAC3HDAC1 | |
| SCHEMBL4224174 | 0.86 | UTS2R (0.49) | UTS2RHIF1AHDAC3HDAC1HDAC2 | |
| SCHEMBL1497206 | 0.86 | UTS2R (0.46) | UTS2RMEN1KMT2AHDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-B1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |