SCHEMBL1497076

SCHEMBL1497076

Cc1cccc(CCNC(=O)NC(CCN(C)C)c2ccc(C(=O)Nc3cscc3N)nc2)c1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
UTS2R Q9UKP6 19/20 0.40
CNR1 P21554 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1483181 0.91 UTS2R (0.47) UTS2R
SCHEMBL10476443 0.88 UTS2R (0.38) UTS2RCNR1
SCHEMBL1497017 0.87 HIF1A (0.46) UTS2R
SCHEMBL1496894 0.87 UTS2R (0.46) UTS2R
SCHEMBL1497037 0.87 UTS2R (0.38) UTS2RCNR1
SCHEMBL1497005 0.87 UTS2R (0.42) UTS2R
SCHEMBL1496979 0.87 UTS2R (0.47) UTS2R
SCHEMBL1497206 0.85 UTS2R (0.46) UTS2RCNR1
SCHEMBL1496939 0.85 UTS2R (0.38) UTS2R
SCHEMBL1496981 0.84 HIF1A (0.44) UTS2RCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2292611-B1 NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE SANTEN PHARMACEUTICAL CO LTD (JP) 2012-07-25 EP disclosed
EP-2292611-A1 NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE Santen Pharmaceutical Co., Ltd (JP) 2011-03-09 EP disclosed