Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 9/20 | 0.56 |
| ▸ | MC5R | P33032 | 9/20 | 0.56 |
| ▸ | MC3R | P41968 | 9/20 | 0.56 |
| ▸ | MC1R | Q01726 | 9/20 | 0.56 |
| ▸ | CTSG | P08311 | 2/20 | 0.54 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.52 |
| ▸ | ITGAV | P06756 | 1/20 | 0.52 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.52 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.52 |
| ▸ | GRB7 | Q14451 | 1/20 | 0.52 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | TSLP | Q969D9 | 5/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908255 | 0.96 | MC4R (0.57) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL12918029 | 0.94 | MC4R (0.57) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL14004103 | 0.94 | MC4R (0.61) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL9908287 | 0.94 | MC4R (0.57) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL15623628 | 0.94 | MC4R (0.57) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL13874838 | 0.94 | MC4R (0.63) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL13246591 | 0.94 | MC4R (0.63) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL12482122 | 0.93 | MC4R (0.57) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL15247336 | 0.93 | MC4R (0.52) | MC4RMC5RMC3RMC1RCTSG | |
| SCHEMBL13485731 | 0.93 | MC4R (0.57) | MC4RMC5RMC3RMC1RCTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166717-A1 | RADIOLABELLING METHOD | GE HEALTHCARE LIMITED (GB) | 2016-06-16 | — | — | US | disclosed |
| US-20160022847-A1 | Radiotracer Compositions | GE HEALTHCARE LIMITED (GB) | 2016-01-28 | — | — | US | disclosed |
| US-9180213-B2 | Radiotracer compositions | GE HEALTHCARE LIMITED (GB) | 2015-11-10 | — | — | US | disclosed |
| US-20140377178-A1 | RADIOFLUORINATION METHOD | UNIVERSITY OF SOUTHAMPTON (GB) | 2014-12-25 | — | — | US | disclosed |
| US-8865125-B2 | Radioiodination method | GE HEALTHCARE LIMITED (GB) | 2014-10-21 | — | — | US | disclosed |
| US-8679455-B2 | Radiolabelling methods | HAMMERSMITH IMANET LIMITED (GB) | 2014-03-25 | — | — | US | disclosed |
| US-20130259804-A1 | RADIOTRACER COMPOSITIONS | GE HEALTHCARE LIMITED (GB) | 2013-10-03 | — | — | US | disclosed |
| US-8530620-B2 | Radiolabelling reagents and methods | GE HEALTHCARE LIMITED (GB) | 2013-09-10 | — | — | US | disclosed |
| US-20130224835-A1 | RADIOLABELLING METHODS | HAMMERSMITH IMANET LIMITED (GB) | 2013-08-29 | — | — | US | disclosed |
| US-8444955-B2 | Radiofluorination methods | GE HEALTHCARE LIMITED (GB) | 2013-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022847-A1 | Radiotracer Compositions | FOLR2, FOLR1, PAICS | MC4R 2453/4885MC5R 2762/4885MC3R 2932/4885 |
| US-20130224835-A1 | RADIOLABELLING METHODS | MPI, VIP, FOLH1 | MC4R 2577/4885MC5R 2811/4885MC3R 2055/4885 |
| US-20130259804-A1 | RADIOTRACER COMPOSITIONS | FOLR2, FOLR1, PAICS | MC4R 2453/4885MC5R 2762/4885MC3R 2932/4885 |
| US-20140377178-A1 | RADIOFLUORINATION METHOD | TFRC, AFF1, AFF2 | MC4R 420/4885MC5R 465/4885MC3R 278/4885 |
| US-20160166717-A1 | RADIOLABELLING METHOD | QPCT, ARF5, PAICS | MC4R 2007/4885MC5R 1280/4885MC3R 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.