Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 6/20 | 0.97 |
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.85 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.85 |
| ▸ | HRH1 | P35367 | 1/20 | 0.85 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.80 |
| ▸ | BACE1 | P56817 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.70 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.70 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899201 | 0.98 | LTA4H (1.00) | LTA4HHRH3KCNH2HRH1HRH4 | |
| SCHEMBL491626 | 0.92 | HRH3 (1.00) | LTA4HHRH3KCNH2HRH1HRH4 | |
| SCHEMBL4094594 | 0.90 | HRH3 (1.00) | LTA4HHRH3KCNH2HRH1HRH4 | |
| SCHEMBL5870409 | 0.90 | LTA4H (0.83) | LTA4HHRH3KCNH2HRH1BACE1 | |
| SCHEMBL3951411 | 0.90 | LTA4H (0.83) | LTA4HHRH3KCNH2HRH1BACE1 | |
| SCHEMBL10679417 | 0.89 | HRH3 (0.97) | LTA4HHRH3KCNH2HRH1HRH4 | |
| Bromide SCHEMBL4827747 | 0.88 | LTA4H (0.81) | LTA4HHRH3KCNH2HRH1BACE1 | |
| Hydrochloric Acid SCHEMBL8475600 | 0.88 | LTA4H (0.81) | LTA4HHRH3KCNH2HRH1BACE1 | |
| SCHEMBL255201 | 0.88 | LTA4H (0.86) | LTA4HHRH3BACE1PSMB1PSMB5 | |
| SCHEMBL10676754 | 0.87 | HRH3 (0.97) | LTA4HHRH3KCNH2HRH1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |