Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | PSMB1 | P20618 | 4/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 4/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 3/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29777398 | 0.85 | ALDH1A1 (0.81) | ALDH1A1TDP1SMN1; SMN2POLBKDM4E | |
| Hydrochloric Acid SCHEMBL9517264 | 0.81 | ALDH1A1 (0.81) | ALDH1A1TDP1SMN1; SMN2POLBKDM4E | |
| SCHEMBL14970708 | 0.77 | ALDH1A1 (0.64) | ALDH1A1TDP1SMN1; SMN2POLBKDM4E | |
| Hydrochloric Acid SCHEMBL14966000 | 0.76 | ALDH1A1 (0.62) | ALDH1A1TDP1SMN1; SMN2POLBKDM4E | |
| SCHEMBL14410108 | 0.75 | TDP1 (0.77) | ALDH1A1TDP1SMN1; SMN2POLB | |
| SCHEMBL23804896 | 0.75 | ALDH1A1 (0.61) | ALDH1A1TDP1SMN1; SMN2POLBHTT | |
| SCHEMBL26580977 | 0.75 | KDM4E (0.60) | ALDH1A1TDP1SMN1; SMN2HTTKDM4E | |
| SCHEMBL11162957 | 0.74 | TSHR (0.58) | TDP1POLBPSMB1PSMB5PSMB2 | |
| SCHEMBL6996167 | 0.73 | ALDH1A1 (0.55) | ALDH1A1TDP1SMN1; SMN2POLBHTT | |
| SCHEMBL13091445 | 0.73 | KDM4E (0.71) | ALDH1A1SMN1; SMN2HTTKDM4EPSMB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |