SCHEMBL14970666

SCHEMBL14970666

Cc1cc(Cl)ccc1OCCCCN1CCCCC1

nearest known ligand 0.75

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.67
KDM4E B2RXH2 1/20 0.67
RECQL P46063 1/20 0.67
LMNA P02545 1/20 0.67
ALDH1A1 P00352 1/20 0.62
MEN1 O00255 1/20 0.62
NPC1 O15118 1/20 0.62
HPGD P15428 1/20 0.62
RAB9A P51151 1/20 0.62
KMT2A Q03164 1/20 0.62
NPSR1 Q6W5P4 1/20 0.62
HRH3 Q9Y5N1 9/20 0.59
L3MBTL1 Q9Y468 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24163824 0.99 KDM4E (0.69) SMN1; SMN2KDM4ERECQLLMNAALDH1A1
SCHEMBL14970479 0.92 SMN1; SMN2 (0.74) SMN1; SMN2KDM4ERECQLLMNAALDH1A1
SCHEMBL15506183 0.86 SMN1; SMN2 (0.83) SMN1; SMN2KDM4ERECQLLMNAALDH1A1
SCHEMBL24163546 0.85 KDM4E (0.70) KDM4ELMNAALDH1A1MEN1KMT2A
SCHEMBL24163009 0.84 SMN1; SMN2 (0.81) SMN1; SMN2KDM4ERECQLLMNAALDH1A1
SCHEMBL24163549 0.84 SMN1; SMN2 (0.73) SMN1; SMN2KDM4ELMNANPC1RAB9A
SCHEMBL7394086 0.84 SMN1; SMN2 (0.73) SMN1; SMN2KDM4ELMNANPC1RAB9A
Hydrochloric Acid SCHEMBL7401914 0.83 SMN1; SMN2 (0.71) SMN1; SMN2KDM4ELMNANPC1RAB9A
SCHEMBL22135588 0.82 KDM4E (0.64) SMN1; SMN2KDM4ELMNAALDH1A1MEN1
SCHEMBL24163541 0.81 ALDH1A1 (0.59) LMNAALDH1A1MEN1KMT2AHRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013074965-A1 AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS MICROBIOTIX, INC. (US) 2013-05-23 WO disclosed