Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
| ▸ | LTA4H | P09960 | 3/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | BACE1 | P56817 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | DRD2 | P14416 | 1/20 | 0.61 |
| ▸ | DRD3 | P35462 | 1/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15474805 | 1.00 | HRH3 (0.76) | HRH3ALDH1A1KDM4EKMT2ALTA4H | |
| Hydrochloric Acid SCHEMBL14966772 | 0.98 | HRH3 (0.74) | HRH3ALDH1A1KDM4EKMT2ALTA4H | |
| SCHEMBL22627324 | 0.90 | HRH3 (0.78) | HRH3ALDH1A1KDM4EKMT2ASMN1; SMN2 | |
| Anisole SCHEMBL28200949 | 0.86 | LTA4H (0.71) | HRH3KMT2ALTA4HBACE1DRD2 | |
| SCHEMBL8785521 | 0.85 | ALDH1A1 (0.61) | HRH3ALDH1A1KDM4EKMT2ALTA4H | |
| SCHEMBL259391 | 0.84 | KDM4E (0.86) | HRH3ALDH1A1KDM4ELTA4HSMN1; SMN2 | |
| SCHEMBL6955456 | 0.84 | LTA4H (0.72) | HRH3LTA4HBACE1 | |
| SCHEMBL14970684 | 0.83 | LTA4H (0.82) | HRH3KDM4ELTA4HDRD3 | |
| SCHEMBL15257179 | 0.83 | LTA4H (0.82) | HRH3KDM4ELTA4HDRD3 | |
| SCHEMBL14970579 | 0.83 | KDM4E (0.81) | HRH3ALDH1A1KDM4ELTA4HSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074965-A1 | AMINOALKYL PHENOL ETHER INHIBITORS OF INFLUENZA A VIRUS | MICROBIOTIX, INC. (US) | 2013-05-23 | — | — | WO | disclosed |