Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14970909 | 0.74 | CYP1A2 (1.00) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7215316 | 0.72 | ALDH1A1 (0.60) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL5801622 | 0.72 | ALDH1A1 (0.63) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL25723979 | 0.71 | ALDH1A1 (0.61) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1520402 | 0.70 | ALDH1A1 (0.80) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL7215334 | 0.70 | MEN1 (0.60) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL14970859 | 0.68 | ALDH1A1 (0.67) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1520491 | 0.68 | MEN1 (0.58) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL10691328 | 0.68 | POLB (0.41) | POLB | |
| SCHEMBL4265964 | 0.64 | CYP1A2 (0.60) | MEN1KMT2AALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074059-A2 | CYTOSINE DEAMINASE MODULATORS FOR ENHANCEMENT OF DNA TRANSFECTION | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2013-05-23 | — | — | WO | disclosed |