Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5069468 | 0.70 | ALDH1A1 (0.59) | POLBSIGMAR1 | |
| SCHEMBL26842409 | 0.70 | SIGMAR1 (0.46) | MAOASIGMAR1 | |
| SCHEMBL6030671 | 0.70 | HSP90AA1 (0.44) | POLBSIGMAR1 | |
| SCHEMBL5298962 | 0.69 | HSD11B1 (0.49) | POLB | |
| SCHEMBL5294911 | 0.69 | HSP90AA1 (0.41) | POLBSIGMAR1 | |
| SCHEMBL5299818 | 0.69 | ALDH1A1 (0.49) | POLB | |
| SCHEMBL28748507 | 0.68 | ALDH1A1 (0.56) | POLB | |
| SCHEMBL1042114 | 0.68 | PRKD3 (0.42) | POLB | |
| SCHEMBL5811783 | 0.68 | TLR8 (0.49) | POLB | |
| SCHEMBL10832722 | 0.68 | SIGMAR1 (0.44) | POLBSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4732989-A | INTERMEDIATES FOR BACTERICIDES | G. D. SEARLE & CO. (US) | 1988-03-22 | — | — | US | disclosed |
| US-4661602-A | ANTIANAEROBIC AGENTS | G. D. SEARLE & CO. (US) | 1987-04-28 | — | — | US | disclosed |