Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | RECQL | P46063 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476427 | 0.87 | UTS2R (0.39) | UTS2RALDH1A1TDP1RECQLL3MBTL1 | |
| SCHEMBL1496910 | 0.86 | UTS2R (0.41) | UTS2RROCK2ROCK1 | |
| SCHEMBL1497044 | 0.85 | UTS2R (0.45) | UTS2RALDH1A1L3MBTL1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL1496948 | 0.84 | UTS2R (0.47) | UTS2RSMN1; SMN2ROCK2ROCK1 | |
| SCHEMBL1497073 | 0.84 | UTS2R (0.47) | UTS2RMEN1KMT2AGAATSHR | |
| SCHEMBL1497187 | 0.84 | UTS2R (0.42) | UTS2RROCK2ROCK1 | |
| Hydrochloric Acid SCHEMBL1497060 | 0.83 | UTS2R (0.47) | UTS2RALDH1A1RECQLKMT2AHTT | |
| SCHEMBL1482616 | 0.83 | UTS2R (0.41) | UTS2RROCK2ROCK1 | |
| SCHEMBL1496897 | 0.83 | UTS2R (0.47) | UTS2RMAPK1ROCK2ROCK1 | |
| SCHEMBL1496971 | 0.83 | UTS2R (0.43) | UTS2RALDH1A1TDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |