Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 7/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.38 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476441 | 0.88 | UTS2R (0.41) | UTS2RPOLBANO1ALDH1A1HPGD | |
| SCHEMBL1497059 | 0.86 | UTS2R (0.47) | UTS2RPOLBALDH1A1HPGD | |
| SCHEMBL1497044 | 0.86 | UTS2R (0.45) | UTS2RALDH1A1KDM4EKMT2AALOX15 | |
| SCHEMBL1497068 | 0.85 | UTS2R (0.47) | UTS2RALDH1A1HPGDKDM4EMEN1 | |
| SCHEMBL1496910 | 0.84 | UTS2R (0.41) | UTS2RROCK2ROCK1 | |
| SCHEMBL1497073 | 0.84 | UTS2R (0.47) | UTS2RMAPK1MEN1KMT2AGAA | |
| SCHEMBL1496981 | 0.83 | HIF1A (0.44) | UTS2RKMT2AGAA | |
| SCHEMBL1497103 | 0.83 | UTS2R (0.42) | UTS2RMAPK1ALDH1A1HPGDKDM4E | |
| Hydrochloric Acid SCHEMBL1496948 | 0.83 | UTS2R (0.47) | UTS2RROCK2ROCK1 | |
| SCHEMBL1483181 | 0.83 | UTS2R (0.47) | UTS2RMEN1KMT2AROCK2ROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2292611-B1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-07-25 | — | — | EP | disclosed |
| EP-2292611-A1 | NOVEL THIOPHENEDIAMINE DERIVATIVE HAVING UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2011-03-09 | — | — | EP | disclosed |