Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 12/20 | 0.52 |
| ▸ | DGAT1 | O75907 | 7/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.45 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.42 |
| ▸ | CBFB | Q13951 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10326024 | 0.88 | NPBWR1 (0.62) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL4559600 | 0.88 | NPBWR1 (0.55) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL14971543 | 0.83 | NPC1 (0.48) | NPBWR1DGAT1CBFB | |
| SCHEMBL14971639 | 0.77 | DGAT1 (0.70) | DGAT1KCNH2SOAT1 | |
| SCHEMBL14971539 | 0.77 | DGAT1 (0.70) | DGAT1KCNH2SOAT1 | |
| SCHEMBL15231992 | 0.76 | DGAT1 (0.47) | NPBWR1DGAT1KCNH2SOAT1CBFB | |
| SCHEMBL10326325 | 0.75 | NPBWR1 (0.55) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL15231864 | 0.75 | NPBWR1 (0.84) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL15245185 | 0.75 | DGAT1 (0.63) | NPBWR1DGAT1KCNH2SOAT1 | |
| SCHEMBL4566490 | 0.74 | NPC1 (0.60) | NPBWR1DGAT1KCNH2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013074387-A1 | IMIDAZOLE DERIVATIVES | MERCK SHARP & DOHME CORP. (US) | 2013-05-23 | — | — | WO | disclosed |