Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.32 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.32 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.31 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PSD | A5PKW4 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15993682 | 1.00 | CYP3A4 (0.39) | CYP3A4KDM4EALDH1A1HTTTDP1 | |
| SCHEMBL15993120 | 1.00 | CYP3A4 (0.39) | CYP3A4KDM4EALDH1A1HTTTDP1 | |
| SCHEMBL14971945 | 0.92 | CYP3A4 (0.39) | CYP3A4KDM4EALDH1A1HTTTDP1 | |
| SCHEMBL14972088 | 0.92 | CYP3A4 (0.39) | CYP3A4KDM4EALDH1A1HTTTDP1 | |
| SCHEMBL18237144 | 0.92 | CYP3A4 (0.39) | CYP3A4KDM4EALDH1A1HTTTDP1 | |
| SCHEMBL15993481 | 0.92 | CYP3A4 (0.39) | CYP3A4KDM4EALDH1A1HTTTDP1 | |
| SCHEMBL14971797 | 0.90 | CYP3A4 (0.36) | CYP3A4KDM4EALDH1A1HTTTDP1 | |
| SCHEMBL14971818 | 0.90 | CYP3A4 (0.36) | CYP3A4KDM4EALDH1A1HTTTDP1 | |
| SCHEMBL15992934 | 0.90 | CYP3A4 (0.39) | CYP3A4KDM4EALDH1A1HTTTDP1 | |
| SCHEMBL14971932 | 0.90 | CYP3A4 (0.39) | CYP3A4KDM4EALDH1A1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2781519-B1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVE AND A PRODUCTION METHOD FOR SAME | ST PHARM CO LTD (KR) | 2019-10-30 | — | — | EP | disclosed |
| US-9499537-B2 | Antiviral pyrrolopyridine derivatives and method for preparing the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-11-22 | — | — | US | disclosed |
| EP-2781519-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVE AND A PRODUCTION METHOD FOR SAME | Korea Research Institute of Chemical Technology (KR) | 2014-09-24 | — | — | EP | disclosed |
| US-20140249162-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVES AND METHOD FOR PREPARING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2014-09-04 | — | — | US | disclosed |
| WO-2013073875-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVE AND A PRODUCTION METHOD FOR SAME | 한국화학연구원 (KR) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249162-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVES AND METHOD FOR PREPARING THE SAME | MAVS, IMPDH1, SARS1 | CYP3A4 1477/4885KDM4E 2672/4885ALDH1A1 2320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.