Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.31 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CASP1 | P29466 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14971818 | 1.00 | CYP3A4 (0.36) | CYP3A4ALDH1A1CYP1A2HPGDMEN1 | |
| SCHEMBL14972088 | 0.92 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL14971945 | 0.92 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL15993481 | 0.92 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL18237144 | 0.92 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDKDM4ESMN1; SMN2 | |
| SCHEMBL15993682 | 0.90 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDKDM4ESLCO1B1 | |
| SCHEMBL14971787 | 0.90 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDKDM4ESLCO1B1 | |
| SCHEMBL15993120 | 0.90 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDKDM4ESLCO1B1 | |
| SCHEMBL14971932 | 0.90 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDKDM4EIDH1 | |
| SCHEMBL15992934 | 0.90 | CYP3A4 (0.39) | CYP3A4ALDH1A1HPGDKDM4EIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9499537-B2 | Antiviral pyrrolopyridine derivatives and method for preparing the same | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2016-11-22 | — | — | US | disclosed |
| US-20140249162-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVES AND METHOD FOR PREPARING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2014-09-04 | — | — | US | disclosed |
| WO-2013073875-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVE AND A PRODUCTION METHOD FOR SAME | 한국화학연구원 (KR) | 2013-05-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140249162-A1 | NOVEL ANTIVIRAL PYRROLOPYRIDINE DERIVATIVES AND METHOD FOR PREPARING THE SAME | MAVS, IMPDH1, SARS1 | CYP3A4 1477/4885ALDH1A1 2320/4885CYP1A2 2277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.