SCHEMBL1497244

SCHEMBL1497244

Cc1cccc(-c2ccccc2)c1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
HSD17B10 Q99714 2/20 0.50
CD44 P16070 1/20 0.50
PDCD1 Q15116 1/20 0.44
CD274 Q9NZQ7 1/20 0.44
CYP2A6 P11509 1/20 0.43
CYP2B6 P20813 1/20 0.43
MYC P01106 1/20 0.42
MAPT P10636 1/20 0.42
HTR7 P34969 1/20 0.42
NPC1 O15118 2/20 0.41
TSHR P16473 2/20 0.41
RAB9A P51151 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
CYP3A4 P08684 2/20 0.41
HPGD P15428 2/20 0.41
MAPK1 P28482 1/20 0.41
CASP3 P42574 1/20 0.41
HBB P68871 1/20 0.41
SENP7 Q9BQF6 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28212899 0.98 ALDH1A1 (0.48) ALDH1A1HSD17B10CD44PDCD1CD274
Hydrochloric Acid SCHEMBL9311004 0.98 ALDH1A1 (0.48) ALDH1A1HSD17B10CD44PDCD1CD274
SCHEMBL3789435 0.84 CD44 (0.48) ALDH1A1HSD17B10CD44MAPTHTR7
SCHEMBL22289770 0.83 CD44 (0.56) ALDH1A1CD44CYP2A6MYCNPC1
SCHEMBL1822460 0.83 ALDH1A1 (0.62) ALDH1A1HSD17B10PDCD1CD274CYP2A6
SCHEMBL30839806 0.83 CD44 (0.62) ALDH1A1CD44CYP2A6MYCNPC1
SCHEMBL3790203 0.83 CD44 (0.62) ALDH1A1CD44CYP2A6MYCNPC1
SCHEMBL2458337 0.82 POLB (0.50) ALDH1A1HSD17B10CD44CYP2A6CYP2B6
SCHEMBL692396 0.81 CD44 (0.54) ALDH1A1CD44MYCHTR7NPC1
SCHEMBL3781453 0.81 MAP4K4 (0.50) ALDH1A1CD44MAPTHTR7NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115626936-B Synthesis method of complex luminescent material capable of finely regulating and controlling luminescence wavelength 五邑大学 2024-05-17 CN claimed
CN-117342955-A Method for preparing 4' -methyl-biphenyl-2-amine 盐城师范学院 2024-01-05 CN claimed
CN-119241435-A 6-Trifluoro methylthiophenanthrene Synthesis method of pyridine compound 西北师范大学 2025-01-03 CN disclosed
CN-117342955-A Method for preparing 4' -methyl-biphenyl-2-amine 盐城师范学院 2024-01-05 CN disclosed
CN-117069724-A Fused ring compounds, pharmaceutical compositions and uses 上海赛默罗德生物科技有限公司 2023-11-17 CN disclosed
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-06-01 US disclosed
CN-115087658-A Sulfonamide or sulfenamide compounds having BRD 4-inducing proteolytic activity, and pharmaceutical use thereof 田边三菱制药株式会社 2022-09-20 CN disclosed
CN-110627721-B Phenanthridine compound and synthesis method thereof 陕西科技大学 2022-06-14 CN disclosed
EP-3613504-A1 PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS Johnson Matthey Public Limited Company (GB) 2020-02-26 EP disclosed
CN-107207470-B Antifungal agent F2G有限公司 2019-12-03 CN disclosed
EP-2585216-B1 PI-ALLYLPALLADIUM AND PI-ALLYLNICKEL COMPLEXES FOR USE AS CATALYSTS IN CARBON-CARBON AND CARBON-NITROGEN COUPLING REACTIONS JOHNSON MATTHEY PLC (GB) 2019-11-20 EP disclosed
US-5489495-A Electrophotographic photoconductor and diamine compounds for use in the same RICHOH COMPANY, LTD. (JP) 1996-02-06 US disclosed
EP-0536151-B1 ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM BOOTS CO PLC (GB) 1994-09-14 EP disclosed
US-5302720-A Biphenyl-substituted guanidine derivatives useful as hypoglycaemic agents THE BOOTS COMPANY (GB) 1994-04-12 US disclosed
EP-0536151-A1 ORTHOSUBSTITUTED BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM. BOOTS CO PLC (GB) 1993-04-14 EP disclosed
WO-1992000273-A1 ORTHOSUBSTITUTED BIPHENYL AMIDINE AND BIPHENYL GUANIDINE DERIVATIVES AND ANTIDIABETIC OR HYPOGLYCAEMIC AGENTS CONTAINING THEM THE BOOTS COMPANY PLC (GB) 1992-01-09 WO disclosed
US-4536591-A Insecticidal [1,1'-biphenyl]-3-ylmethyl esters FMC CORPORATION (US) 1985-08-20 US disclosed
US-4402973-A Insecticidal (1,1'-biphenyl)-3-ylmethyl esters FMC CORPORATION (US) 1983-09-06 US disclosed
US-4329518-A INSECTICIDES, ACARICIDES, MITICIDES FMC CORPORATION (US) 1982-05-11 US disclosed
EP-0049977-A1 Insecticidal (1,1'-biphenyl)-3-ylmethyl esters, their production and use and compositions containing them FMC Corporation (US) 1982-04-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230167145-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, OSBP ALDH1A1 263/4885HSD17B10 1595/4885CD44 3848/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.