SCHEMBL2458337

SCHEMBL2458337

Cc1ccc(-c2ccccc2)c(N)c1N

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.50
ALDH1A1 P00352 2/20 0.46
CYP3A4 P08684 2/20 0.46
NPC1 O15118 1/20 0.46
TSHR P16473 1/20 0.46
MAPK1 P28482 1/20 0.46
CASP3 P42574 1/20 0.46
RAB9A P51151 1/20 0.46
HBB P68871 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ESR2 Q92731 1/20 0.45
HSD17B10 Q99714 2/20 0.44
CYP2A6 P11509 1/20 0.43
CYP2B6 P20813 1/20 0.43
MAPT P10636 2/20 0.42
CD44 P16070 1/20 0.39
PDE4A P27815 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9578659 0.89 ALDH1A1 (0.50) POLBALDH1A1CYP3A4NPC1TSHR
SCHEMBL4107003 0.85 ALDH1A1 (0.57) ALDH1A1CYP3A4TSHRMAPK1SMN1; SMN2
SCHEMBL10935618 0.84 POLB (0.67) POLBALDH1A1CYP3A4NPC1TSHR
SCHEMBL692397 0.84 POLB (0.48) POLBALDH1A1CYP3A4NPC1TSHR
SCHEMBL31111778 0.84 POLB (0.48) POLBALDH1A1CYP3A4NPC1TSHR
SCHEMBL27685032 0.83 NPC1 (0.52) POLBALDH1A1CYP3A4NPC1TSHR
SCHEMBL1497244 0.82 ALDH1A1 (0.50) POLBALDH1A1CYP3A4NPC1TSHR
SCHEMBL28621175 0.82 NPC1 (0.47) POLBALDH1A1CYP3A4NPC1TSHR
SCHEMBL9561614 0.81 POLB (0.45) POLBALDH1A1CYP3A4NPC1TSHR
SCHEMBL20657073 0.80 HSD17B10 (0.57) ALDH1A1CYP3A4NPC1MAPK1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8278820-B2 Active matrix organic electroluminescent device and method of manufacture thereof University of Electric Sience and Technology of China (CN) 2012-10-02 US claimed
US-20110221331-A1 Active matrix organic electroluminescent device and method of manufacture thereof UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA 2011-09-15 US claimed
US-8771809-B2 Photoalignment material, display substrate having an alignment layer formed using the same, and method of manufacturing the display substrate SAMSUNG DISPLAY CO., LTD. (KR) 2014-07-08 US disclosed
US-8476824-B2 Active matrix organic electroluminescent device and method of manufacture thereof UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA (CN) 2013-07-02 US disclosed
US-8278820-B2 Active matrix organic electroluminescent device and method of manufacture thereof University of Electric Sience and Technology of China (CN) 2012-10-02 US disclosed
US-20120164762-A1 Active matrix organic electroluminescent device and method of manufacture thereof UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA 2012-06-28 US disclosed
US-20110221331-A1 Active matrix organic electroluminescent device and method of manufacture thereof UNIVERSITY OF ELECTRONIC SCIENCE AND TECHNOLOGY OF CHINA 2011-09-15 US disclosed
US-20090237603-A1 PHOTOALIGNMENT MATERIAL, DISPLAY SUBSTRATE HAVING AN ALIGNMENT LAYER FORMED USING THE SAME, AND METHOD OF MANUFACTURING THE DISPLAY SUBSTRATE SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-09-24 US disclosed
EP-1263478-A2 FUNCTIONAL RADIOGRAPHIC IMAGING METHODS AND AGENTS Veritas Pharmaceuticals (US) 2002-12-11 EP disclosed
EP-1263324-A2 RADIOGRAPHIC ASSESSMENT OF TISSUE RESPONSE TO COMPOUNDS Veritas Pharmaceuticals (US) 2002-12-11 EP disclosed
WO-2001068151-A2 FUNCTIONAL RADIOGRAPHIC IMAGING METHODS AND AGENTS VERITAS PHARMACEUTICALS (US) 2001-09-20 WO disclosed
WO-2001067958-A2 RADIOGRAPHIC ASSESSMENT OF TISSUE RESPONSE TO COMPOUNDS VERITAS PHARMACEUTICALS (US) 2001-09-20 WO disclosed