Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL28259477 | 0.95 | ALDH1A1 (0.32) | ALDH1A1 | |
| Acetic Acid SCHEMBL28181036 | 0.95 | FFAR3 (0.35) | ALDH1A1HSD17B10TDP1TSHRLMNA | |
| Vinyl Chloride SCHEMBL10951201 | 0.95 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TDP1TSHR | |
| Vinyl Chloride SCHEMBL7052380 | 0.95 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TDP1TSHR | |
| Vinyl Chloride SCHEMBL4992443 | 0.95 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TDP1TSHR | |
| Vinyl Chloride SCHEMBL15910987 | 0.95 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TDP1TSHR | |
| Vinyl Chloride SCHEMBL8398856 | 0.95 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TDP1TSHR | |
| Vinyl Chloride SCHEMBL8397531 | 0.95 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TDP1TSHR | |
| Vinyl Chloride SCHEMBL6231138 | 0.95 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TDP1TSHR | |
| Vinyl Chloride SCHEMBL7758502 | 0.95 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2091733-B1 | MULTI-LAYER COATED PRODUCT AND PREPARATION METHOD THEREOF | BYD CO LTD (CN) | 2013-05-29 | — | — | EP | disclosed |