Bicarbonate

Bicarbonate

SCHEMBL28259477

C=CCl.C=COC(C)=O.O=C(O)Cl.O=C(O)O

nearest known ligand 0.32

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Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL14972727 0.95 ALDH1A1 (0.35) ALDH1A1
SCHEMBL28259471 0.93 ALDH1A1 (0.36) ALDH1A1
SCHEMBL27258363 0.93 ALDH1A1 (0.36) ALDH1A1
Acetic Acid SCHEMBL28181036 0.91 FFAR3 (0.35) ALDH1A1
Vinyl Chloride SCHEMBL15910987 0.91 ALDH1A1 (0.38) ALDH1A1
Vinyl Chloride SCHEMBL10951201 0.91 ALDH1A1 (0.38) ALDH1A1
Vinyl Chloride SCHEMBL8398856 0.91 ALDH1A1 (0.38) ALDH1A1
Vinyl Chloride SCHEMBL7758502 0.91 ALDH1A1 (0.38) ALDH1A1
Vinyl Chloride SCHEMBL8397531 0.91 ALDH1A1 (0.38) ALDH1A1
Vinyl Chloride SCHEMBL7052380 0.91 ALDH1A1 (0.38) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108864031-A A kind of preparation method of vinylene carbonate 福建博鸿新能源科技有限公司 2018-11-23 CN disclosed