Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL399162 | 0.71 | SMN1; SMN2 (0.56) | SMN1; SMN2MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL6866606 | 0.70 | MAOA (0.57) | SMN1; SMN2MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL6866612 | 0.70 | MAOA (0.57) | SMN1; SMN2MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL14972752 | 0.70 | HSP90AA1 (0.49) | SMN1; SMN2MAOAMAOBALDH1A1KDM4E | |
| Ethyne SCHEMBL1922812 | 0.68 | SMN1; SMN2 (0.53) | SMN1; SMN2MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL12614725 | 0.68 | MAOA (0.53) | SMN1; SMN2MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL26780011 | 0.68 | MAOA (0.53) | SMN1; SMN2MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL14465565 | 0.68 | MAOA (0.53) | SMN1; SMN2MAOAMAOBALDH1A1KDM4E | |
| SCHEMBL13640180 | 0.67 | POLB (0.43) | SMN1; SMN2MAOAMAOBALDH1A1KDM4E | |
| Bromide SCHEMBL9508770 | 0.66 | MAOA (0.52) | SMN1; SMN2MAOAMAOBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2391614-B1 | ENAMINOCARBONYL COMPOUNDS AND THEIR USE | INST CHEMII ORGANICZNEJ POLSKA AKADEMIA NAUK (PL) | 2013-05-29 | — | — | EP | disclosed |