Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14972834 | 0.94 | MAPT (0.43) | MAPTFAAHTP53LMNAHTT | |
| SCHEMBL14972825 | 0.88 | MAPT (0.47) | MAPTFAAHKDM4ETP53PKM | |
| SCHEMBL4083537 | 0.80 | FAAH (0.54) | MAPTFAAHLMNAHTT | |
| SCHEMBL2169462 | 0.79 | FAAH (0.65) | MAPTFAAHPKMLMNACYP1A2 | |
| SCHEMBL2160503 | 0.78 | FAAH (0.50) | MAPTFAAHKDM4ETP53PKM | |
| SCHEMBL2993129 | 0.78 | FAAH (0.51) | MAPTFAAHLMNAHTT | |
| SCHEMBL4378390 | 0.75 | FAAH (0.48) | MAPTFAAHKDM4EPKM | |
| SCHEMBL3847524 | 0.74 | FAAH (0.54) | MAPTFAAHKDM4ETP53PKM | |
| SCHEMBL5773330 | 0.73 | MAPT (0.56) | MAPTFAAHKDM4ETP53PKM | |
| SCHEMBL3008722 | 0.73 | FAAH (0.51) | MAPTFAAHPKMLMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809279-B1 | PARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INT (US) | 2013-05-29 | — | — | EP | claimed |