Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14972847 | 0.94 | MAPT (0.47) | MAPTLMNAHTTFAAHTP53 | |
| SCHEMBL14972825 | 0.81 | MAPT (0.47) | MAPTLMNAFAAHTP53NAMPT | |
| SCHEMBL5779675 | 0.73 | S1PR3 (0.53) | MAPTS1PR3 | |
| SCHEMBL4083537 | 0.73 | FAAH (0.54) | MAPTLMNAHTTFAAH | |
| SCHEMBL2169462 | 0.72 | FAAH (0.65) | MAPTLMNAFAAH | |
| SCHEMBL2993129 | 0.72 | FAAH (0.51) | MAPTLMNAHTTFAAH | |
| SCHEMBL2160503 | 0.71 | FAAH (0.50) | MAPTLMNAFAAHTP53 | |
| SCHEMBL6255149 | 0.70 | TUBB4A (0.48) | MAPTLMNAFAAHTP53 | |
| SCHEMBL3847524 | 0.69 | FAAH (0.54) | MAPTLMNAFAAHTP53NAMPT | |
| SCHEMBL4378390 | 0.69 | FAAH (0.48) | MAPTFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809279-B1 | PARTICULATE COMPOSITIONS OF TUBULIN INHIBITOR | BAXTER INT (US) | 2013-05-29 | — | — | EP | claimed |