SCHEMBL1497300

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1001695	0.93	ADORA2B (0.51)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL1497281	0.92	ADORA2B (0.48)	ADORA2BADORA2AADORA1KDM4EALDH1A1
	SCHEMBL1497235	0.89	ADORA2B (0.65)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL1497292	0.87	ADORA2B (0.47)	ADORA2BADORA2AADORA1KDM4EALDH1A1
	SCHEMBL12094031	0.86	ADORA2B (0.53)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL23860290	0.85	ADORA2B (0.47)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL30266890	0.85	ADORA2B (0.47)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL9885735	0.85	ADORA2B (0.50)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL9885736	0.85	ADORA2B (0.50)	ADORA2BADORA2AADORA1KDM4EMEN1
	SCHEMBL9885738	0.84	ADORA2B (0.50)	ADORA2BADORA2AADORA1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.