Sulfathiourea

Sulfathiourea

SCHEMBL149742

NC(=S)NS(=O)(=O)c1ccc(N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.61
TDP1 Q9NUW8 2/20 0.61
DHFR P00374 1/20 0.61
SMN1; SMN2 Q16637 1/20 0.61
CA1 P00915 6/20 0.59
CA2 P00918 6/20 0.59
MMP1 P03956 1/20 0.59
MMP2 P08253 1/20 0.59
MMP9 P14780 1/20 0.59
MMP8 P22894 1/20 0.59
MMP13 P45452 1/20 0.59
ALDH1A1 P00352 3/20 0.56
F2 P00734 2/20 0.55
PRSS1 P07477 2/20 0.55
PRSS2 P07478 2/20 0.55
PRSS3 P35030 2/20 0.55
LMNA P02545 3/20 0.54
KMT2A Q03164 2/20 0.54
MEN1 O00255 1/20 0.54
FBP1 P09467 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfathiourea SCHEMBL152438 0.83 CA2 (0.56) TSHRTDP1DHFRSMN1; SMN2CA1
SCHEMBL7363066 0.82 ALDH1A1 (0.60) SMN1; SMN2CA1CA2MMP1MMP2
Sulfacarbamide SCHEMBL154846 0.82 TSHR (0.69) TSHRTDP1DHFRSMN1; SMN2CA1
SCHEMBL728028 0.82 CA2 (0.59) CA1CA2MMP1MMP2MMP9
Sulfaguanidine SCHEMBL93639 0.80 TSHR (0.61) TSHRTDP1DHFRSMN1; SMN2CA1
Sulfaguanidine SCHEMBL4347029 0.80 TSHR (0.61) TSHRTDP1DHFRSMN1; SMN2CA1
SCHEMBL18296817 0.80 TSHR (0.61) TSHRTDP1DHFRSMN1; SMN2CA1
Sulfaguanidine SCHEMBL28627621 0.78 TSHR (0.59) TSHRTDP1DHFRSMN1; SMN2CA1
Sulfaguanidine SCHEMBL28848861 0.78 TSHR (0.59) TSHRTDP1DHFRSMN1; SMN2CA1
Sulfaguanidine SCHEMBL11754909 0.78 TSHR (0.59) TSHRTDP1DHFRSMN1; SMN2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1487 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12274830-B2 Nitric oxide inhalation therapy for infants with bronchiolitis BEYOND AIR LTD (IL) 2025-04-15 US claimed
US-20250099557-A1 ANTIBIOTIC PHARMACEUTICAL COMPOSITION CAPABLE OF SUBCUTANEOUS ADMINISTRATION SHANGHAI BAO PHARMACEUTICALS CO., LTD. (CN) 2025-03-27 US claimed
US-20240173512-A1 METHODS FOR POTENTIATING ANTIMICROBIAL AGENTS STREETERVILLE CAPITAL, LLC 2024-05-30 US claimed
EP-4374848-A1 ANTIBIOTIC PHARMACEUTICAL COMPOSITION CAPABLE OF SUBCUTANEOUS ADMINISTRATION Shanghai Bao Pharmaceuticals Co., Ltd. (CN) 2024-05-29 EP claimed
CN-117858696-A Antibiotic pharmaceutical composition capable of subcutaneous administration 上海宝济药业股份有限公司 2024-04-09 CN claimed
US-11890421-B2 Methods for potentiating antimicrobial agents BEYOND AIR LTD (IL) 2024-02-06 US claimed
WO-2023001264-A1 ANTIBIOTIC PHARMACEUTICAL COMPOSITION CAPABLE OF SUBCUTANEOUS ADMINISTRATION 上海宝济药业有限公司 2023-01-26 WO claimed
CN-113559264-A Methods of treating microbial infections including mastitis 罗达制药公司 2021-10-29 CN claimed
CN-113144197-A Method of treating topical microbial infections 罗达制药公司 2021-07-23 CN claimed
EP-3721985-A1 MOLECULARLY IMPRINTED POLYMERS SENSORS FOR SULFONAMIDES Tallinn University of Technology (EE) 2020-10-14 EP claimed
US-5543417-A 5 Alpha-reductase inhibitor and at least one of an antibacterial agent, a keratolytic agent or an anti-inflammatory agent MERCK & CO., INC. (US) 1996-08-06 US claimed
WO-1996012487-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1996012817-A1 COMBINATION METHOD FOR ACNE TREATMENT MERCK & CO., INC. (US) 1996-05-02 WO claimed
WO-1995020387-A1 METHOD FOR PREVENTING OR REDUCING PHOTOSENSITIVITY AND/OR PHOTOTOXICITY REACTIONS TO MEDICATIONS G.D. SEARLE & CO. (US) 1995-08-03 WO claimed
EP-0572560-A4 USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY. SHAPIRO HOWARD K (US) 1995-04-26 EP claimed
US-5374608-A Compositions containing adducts and surfactants UNION OIL COMPANY OF CALIFORNIA (US) 1994-12-20 US claimed
US-5288692-A Systemic herbicides and methods of use UNION OIL COMPANY OF CALIFORNIA (US) 1994-02-22 US claimed
EP-0572560-A1 USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY SHAPIRO, Howard, K. (US) 1993-12-08 EP claimed
WO-1992014456-A1 USE OF PHARMACEUTICAL COMPOUNDS IN THE TREATMENT OF SYMPTOMS OF DISORDERS RELATED TO NEUROLOGICAL DISEASES AND ETIOLOGICALLY RELATED SYMPTOMOLOGY SHAPIRO HOWARD K (US) 1992-09-03 WO claimed
US-4661340-A Quail egg based stabilized foam compositions for cosmetic purposes INTERKEMIA VEGYIPARI GAZDASAGI TARSASAG (HU) 1987-04-28 US claimed