Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.51 |
| ▸ | RARA | P10276 | 7/20 | 0.50 |
| ▸ | IKBKB | O14920 | 3/20 | 0.50 |
| ▸ | RARG | P13631 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2393233 | 0.85 | RARB (0.55) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL14974756 | 0.85 | IKBKB (0.48) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL2390175 | 0.84 | RARB (0.54) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL2390151 | 0.84 | RARB (0.51) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL14974248 | 0.83 | HDAC11 (0.43) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL2391808 | 0.83 | PTPN11 (0.54) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL1913992 | 0.82 | RARB (0.52) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL2391578 | 0.82 | PTPN11 (0.53) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL2391094 | 0.81 | PTPN11 (0.68) | RARBRARARARGMEN1KMT2A | |
| SCHEMBL2395883 | 0.81 | PTPN11 (0.52) | RARBRARAIKBKBRARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096544-B2 | Therapeutic compounds | WAYNE STATE UNIVERSITY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130137699-A1 | THERAPEUTIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2013-05-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137699-A1 | THERAPEUTIC COMPOUNDS | BAX, MCL1, TMBIM6 | RARB 3599/4885RARA 3485/4885IKBKB 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.