Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 8/20 | 0.52 |
| ▸ | RARA | P10276 | 7/20 | 0.51 |
| ▸ | IKBKB | O14920 | 3/20 | 0.51 |
| ▸ | RARG | P13631 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | NR0B2 | Q15466 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1914337 | 0.92 | RARB (0.47) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL14974800 | 0.90 | RARA (0.52) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL1914085 | 0.86 | IKBKB (0.51) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL1914098 | 0.84 | RARB (0.53) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL1914439 | 0.84 | XDH (0.43) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL1914172 | 0.84 | RARB (0.50) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL1914166 | 0.83 | IKBKB (0.42) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL14974372 | 0.82 | RARB (0.51) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL1914227 | 0.82 | IKBKB (0.51) | RARBRARAIKBKBRARGMEN1 | |
| SCHEMBL14973916 | 0.82 | RARB (0.73) | RARBRARAIKBKBRARGMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096544-B2 | Therapeutic compounds | WAYNE STATE UNIVERSITY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130137699-A1 | THERAPEUTIC COMPOUNDS | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2013-05-30 | — | — | US | disclosed |
| WO-2011079305-A1 | THERAPEUTIC COMPOUNDS | WAYNE STATE UNIVERSITY (US) | 2011-06-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137699-A1 | THERAPEUTIC COMPOUNDS | BAX, MCL1, TMBIM6 | RARB 3599/4885RARA 3485/4885IKBKB 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.