Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.48 |
| ▸ | CDC25B | P30305 | 3/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | NQO2 | P16083 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.40 |
| ▸ | TUBB | P07437 | 1/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408683 | 0.81 | CYP1A2 (0.44) | CYP1A2CYP2A6CDC25BCASP3SENP7 | |
| SCHEMBL4600762 | 0.80 | CYP1A2 (0.52) | CYP1A2CYP2A6MAPTKDM4ECYP3A4 | |
| SCHEMBL29469023 | 0.76 | CDC25B (0.50) | CYP1A2CYP2A6CDC25BCASP3SENP7 | |
| SCHEMBL2201994 | 0.76 | CDC25B (0.50) | CYP1A2CYP2A6CDC25BCASP3SENP7 | |
| SCHEMBL29955307 | 0.76 | CDC25B (0.50) | CYP1A2CYP2A6CDC25BCASP3SENP7 | |
| SCHEMBL1161428 | 0.75 | CYP2A6 (0.57) | CYP1A2CYP2A6CDC25BCASP3SENP7 | |
| SCHEMBL5344059 | 0.75 | ALDH1A1 (0.48) | CYP1A2CYP2A6NQO1MAPTKDM4E | |
| SCHEMBL5782272 | 0.75 | CYP1A2 (0.54) | CYP1A2CYP2A6CDC25BCASP3SENP7 | |
| SCHEMBL16494278 | 0.75 | CYP2A6 (0.57) | CYP1A2CYP2A6MAPTKDM4EALDH1A1 | |
| SCHEMBL443362 | 0.75 | NQO1 (0.57) | CYP1A2CYP2A6CDC25BCASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782916-B1 | CARBOXY X RHODAMINE ANALOGS | PROMEGA CORP (US) | 2018-02-28 | — | — | EP | disclosed |
| US-20160320372-A1 | CARBOXY X RHODAMINE ANALOGS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-11-03 | — | — | US | disclosed |
| US-20150260725-A1 | CARBOXY X RHODAMINE ANALOGS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2015-09-17 | — | — | US | disclosed |
| US-9056885-B2 | Carboxy X rhodamine analogs | PROMEGA CORPORATION (US) | 2015-06-16 | — | — | US | disclosed |
| EP-2782916-A1 | CARBOXY X RHODAMINE ANALOGS | Promega Corporation (US) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013078244-A1 | CARBOXY X RHODAMINE ANALOGS | PROMEGA CORPORATION (US) | 2013-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160320372-A1 | CARBOXY X RHODAMINE ANALOGS | PRCP, CPA3, CPA4 | CYP1A2 1853/4885CYP2A6 1896/4885CDC25B 4176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.