Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 5/20 | 0.49 |
| ▸ | ALOX15B | O15296 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28832462 | 0.77 | NOTUM (0.51) | L3MBTL1ALOX15BALDH1A1HTT | |
| SCHEMBL25442240 | 0.75 | NOTUM (0.46) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL17819307 | 0.75 | CYP19A1 (0.46) | — | |
| SCHEMBL5173638 | 0.74 | FDPS (0.47) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL21102340 | 0.74 | CYP3A4 (0.46) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL2336960 | 0.74 | CYP3A4 (0.69) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL353826 | 0.74 | CYP3A4 (0.50) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL18419903 | 0.74 | CYP3A4 (0.50) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL10469438 | 0.74 | CYP3A4 (0.46) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 | |
| SCHEMBL1407881 | 0.74 | CYP3A4 (0.46) | CYP3A4L3MBTL1CYP1A2CYP2D6CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113861192-A | Preparation method of C-3 halogenated imidazo [1,2-a ] pyridine derivative | 郑州大学 | 2021-12-31 | — | — | CN | disclosed |
| CN-105793256-B | Imdazole derivatives | 豪夫迈·罗氏有限公司 | 2019-09-10 | — | — | CN | disclosed |
| CN-108473502-A | 4, 6-dihydropyrrolo [3,4-C ] pyrazole-5 (1H) -carbonitrile derivatives for the treatment of cancer | 特殊治疗有限公司 | 2018-08-31 | — | — | CN | disclosed |
| CN-105793256-A | Imidazole derivatives | 豪夫迈·罗氏有限公司 | 2016-07-20 | — | — | CN | disclosed |
| CN-104822679-A | Imidazopyridine derivatives | HOFFMANN LA ROCHE | 2015-08-05 | — | — | CN | disclosed |
| WO-2013077654-A1 | IRIDIUM (III) COMPLEX AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME | 주식회사 두산 (KR) | 2013-05-30 | — | — | WO | disclosed |
| CN-103097384-A | Substituted imidazo [1,2-a ] pyrimidines and pyridines | BAYER IP GMBH | 2013-05-08 | — | — | CN | disclosed |