Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2686005 | 0.86 | NAAA (0.46) | NAAA | |
| SCHEMBL2687163 | 0.86 | NAAA (0.46) | NAAA | |
| SCHEMBL22769453 | 0.78 | CYP3A4 (0.39) | TSHRALDH1A1CA2 | |
| SCHEMBL819199 | 0.78 | ALDH1A1 (0.44) | NPSR1EPHX2TSHRKDM4EALDH1A1 | |
| SCHEMBL819467 | 0.77 | NPSR1 (0.44) | NPSR1EPHX2SMN1; SMN2TSHREPHX1 | |
| SCHEMBL1698457 | 0.77 | EPHX1 (0.48) | NPSR1EPHX2SMN1; SMN2EPHX1ALDH1A1 | |
| SCHEMBL819198 | 0.77 | NPSR1 (0.41) | NPSR1EPHX2SMN1; SMN2SHBGTSHR | |
| SCHEMBL12401977 | 0.77 | NPSR1 (0.44) | NPSR1EPHX2SMN1; SMN2TSHREPHX1 | |
| SCHEMBL2343300 | 0.76 | CYP3A4 (0.40) | TSHRALDH1A1CA1CA2 | |
| SCHEMBL888576 | 0.76 | CYP2D6 (0.43) | NPSR1TSHRKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782938-A1 | HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME | BASF Corporation (US) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013077837-A1 | HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME | BASF CORPORATION (US) | 2013-05-30 | — | — | WO | disclosed |