Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 6/20 | 0.68 |
| ▸ | TNF | P01375 | 2/20 | 0.56 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.56 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | GALR3 | O60755 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14977486 | 0.89 | RAB9A (0.62) | DHODHTNFNR2F2NOD1POLB | |
| SCHEMBL14977635 | 0.89 | KMT2A (0.59) | DHODHKMT2AMEN1 | |
| SCHEMBL14977504 | 0.88 | DHODH (0.68) | DHODHTNFNR2F2NOD1POLB | |
| SCHEMBL14985372 | 0.88 | KMT2A (0.57) | DHODHTNFNR2F2NOD1POLB | |
| SCHEMBL14977788 | 0.85 | DHODH (0.69) | DHODHKMT2AMEN1 | |
| SCHEMBL14977360 | 0.84 | NPC1 (0.56) | DHODHTNFNR2F2NOD1POLB | |
| SCHEMBL14977709 | 0.83 | RAB9A (0.64) | DHODHTNFNR2F2NOD1POLB | |
| SCHEMBL14977157 | 0.82 | DHODH (0.56) | DHODHTNFNR2F2NOD1KMT2A | |
| SCHEMBL14977713 | 0.82 | RAB9A (0.64) | DHODHTNFNR2F2NOD1KMT2A | |
| SCHEMBL14977161 | 0.82 | RAB9A (0.64) | DHODHTNFNR2F2NOD1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2782943-A1 | CURABLE COMPOSITIONS CONTAINING ISOCYANATE FUNCTIONAL COMPONENTS AND HAVING IMPROVED DURABILITY IN THE CURED STATE | Dow Global Technologies LLC (US) | 2014-10-01 | — | — | EP | disclosed |
| WO-2013077908-A1 | CURABLE COMPOSITIONS CONTAINING ISOCYANATE FUNCTIONAL COMPONENTS AND HAVING IMPROVED DURABILITY IN THE CURED STATE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |