Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | DHODH | Q02127 | 10/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TTR | P02766 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14985372 | 0.90 | KMT2A (0.57) | KMT2AMEN1DHODH | |
| SCHEMBL14977504 | 0.90 | DHODH (0.68) | KMT2AMEN1DHODH | |
| SCHEMBL14977149 | 0.89 | DHODH (0.68) | KMT2AMEN1DHODH | |
| SCHEMBL14977713 | 0.88 | RAB9A (0.64) | KMT2AMEN1DHODHTTRATM | |
| SCHEMBL14977788 | 0.87 | DHODH (0.69) | KMT2AMEN1DHODHGAASMN1; SMN2 | |
| SCHEMBL14977822 | 0.86 | KMT2A (0.56) | KMT2AMEN1DHODHGAASMN1; SMN2 | |
| SCHEMBL14977664 | 0.85 | DHODH (0.54) | KMT2AMEN1DHODHTTR | |
| SCHEMBL14977820 | 0.84 | DHODH (0.66) | KMT2AMEN1DHODH | |
| SCHEMBL14985332 | 0.84 | KMT2A (0.58) | KMT2AMEN1DHODH | |
| SCHEMBL14977362 | 0.84 | KMT2A (0.56) | KMT2AMEN1DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |
| WO-2013078413-A1 | MODULATORS OF LIPID STORAGE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-05-30 | — | — | WO | disclosed |